产品货号：
Z10121
中文名称：
5 Lipoxygenase/ALOX5抗体
英文名称：
Anti-5 Lipoxygenase/ALOX5 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-5 Lipoxygenase/ALOX5 Antibody |
| 指标别名 | 5 Lipoxygenase;5 LO;5 LOX;5LPG;ALOX5;LOG5 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | IHC,WB |
| 基因名称 | ALOX5 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human ALOX5 recombinant protein (Position:A120-R483).Human ALOX5 shares 94% amino acid (aa) sequence identity with both mouse and rat ALOX5. |
| 实际分子量 | 78KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Arachidonate 5-lipoxygenase,also known as 5-LOX or 5-LO,is an enzyme that in humans is encoded by the ALOX5 gene.ALOX5 is a member of the lipoxygenase family of enzymes.It is mapped to 10q11.21.ALOX5 plays a dual role in the synthesis of leukotrienes from arachidonic acid.The position of ALOX5 within the nucleus of resting cells determines the capacity to generate LTB4 upon subsequent activation.It is involved in lung vascular tone regulation and in the development of chronic pulmonary hypertension in hypoxic rodent models.ALOX5 also transforms EFAs into leukotrienes and is a current target for pharmaceutical intervention in a number of diseases. |
| Uniprot ID | P09917 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | arachidonate 5-lipoxygenase |
| 蛋白名全称 | Arachidonate 5-lipoxygenase |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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